He is despised and rejected of men; a man of sorrows, and acquainted with grief: and we hid as it were our faces from him; he was despised, and we esteemed him not. (Isaiah 53:3 KJV)
Throughout Isaiah 53, Isaiah painted this suffering servant, who faced too many rejection and mock by his people. Of course, God gave Isaiah a vision of Jesus' last week on the earth. His last week on Earth didn't go well. One time, people followed Him around. Not because of His messages, but of His miracle working hands. They wanted Him to perform miracle to heal their sicknesses and fill their empty stomachs. At one time, they cried to Him, "Hosanna (see Matthew 21:9, 15; Mark 11:9-10; John 12:13)." People praised Him as a King, who would govern the land, not as Savior of this corrupted world. But at His final hours, Jesus faced most horrific capitol punishment because of rejections that He received from His people. People thought that He was going to be their King of the land. But as more people hear the messages, they believed that He constricted against the Words of God, even they have waited for Him to return to them so long.
John 1:11 says, "He came unto his own, and his own received him not." How you feel if your people just ignore you? Even Prophet Jeremiah felt the pain when his people mocked him as he shared the warning from the Words of God. It was very devastating situation. For Jesus, it was more devastating situation. Not only He spent sometimes in jail, He had to face many slaps on His back with string and then final punishment for Him to face the death on the cross. Even Jesus faced many rejections throughout His life, He didn't turn against His people. Instead, He took our sins for us at the Calvary, so that we can establish our relationship with Him forever.